CONSIDERATIONS TO KNOW ABOUT MESENCHYMAL STEM CELLS (MSCS)

In contrast to investigations describing the pro-angiogenic impact of MSCs (Zhang et al., 2013; Li et al., 2016), the anti-tumor activity of MSCs through inhibition of tumor angiogenesis has also been documented. A study claimed that bone marrow MSCs limit vascular development in ΔGli36 glioma xenograft by means of downregulation of the PDGF/PDGFR

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